منابع مشابه
Inotropic action of hexamethonium.
The positive inotropic action of hexainethoniuin in hypodynamic and freshly prepared papillary muscles of the cat and the hypodynamic heart-lung preparation of the dog has been demonstrated. Within certain limits, there exists a proportionality between the concentration of hexamethonium and the magnitude of the inotropic response. In both preparations results have been obtained which indicate t...
متن کاملHexamethonium and glaucoma.
THIS investigation was undertaken in an endeavour to decide if the methonium ganglion blocking compounds could be administered to cases of vascular hypertension who were known to be suffering from glaucoma, or to similar vascular hypertensive cases of a glaucomatous disposition although this might not be known, without the danger of subsequent sequelae such as an increase in intra-ocular pressu...
متن کاملThe hexamethonium asthma study and the death of a normal volunteer in research.
Ellen Roche was a 24 year old technician from the Johns Hopkins Asthma and Allergy Centre who volunteered to take part in a study designed to provoke a mild asthma attack in order to help doctors discover the reflex that protects the lungs of healthy people against asthma attacks. After inhaling hexamethonium, a medication used for treating high blood pressure in the 1950s and 60s, Ms Roche bec...
متن کاملProtein in meconium from meconium ileus.
Meconium ileus is the earliest manifestation of cystic fibrosis, and several investigations have been undertaken to determine its cause. In 1952, Buchanan and Rapoport showed that the ash content of abnormal meconium was twice as high as that ofnormal newborns, and that whereas normal meconium consisted of only 7% protein, this rose to 85% in meconium ileus. We here show that the proteins conce...
متن کاملLung changes during hexamethonium therapy for hypertension.
During the course of treating 54 severely hypertensive patients with parenteral hexamethonium bromide, wehave observed the development of unexpected pulmonary dyspnea and associated radiographic changes in the lungs in three cases after 7, 9, and 12 months' therapy respectively. Two of these came to autopsy; the third has recovered. The object of this paper is to record the clinical, radiologic...
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ژورنال
عنوان ژورنال: BMJ
سال: 1955
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4912.522